Aggregate Degradation for Alzheimer's

Sally Zhang  is a junior who is majoring in Biology. She was awarded a Fall 2018 Independent Grant which she used to conduct research on ubiquination and Alzheimer's disease under Dr. Hyojung Choo. 

I started doing my project at the Seyfried Lab of the Biochemistry department and Center for Neurodegenerative diseases of Emory School of Medicine in April 2018. My project aims to examine the mechanisms underlying the turnover of insoluble neurofibrillary tangles of Tau, a key type of pathological protein aggregate in Alzheimer’s disease. Alzheimer’s disease is characterized by the presence of protein aggregates and a loss of protein homeostasis. Ubiquitin (Ub) is a 76 amino acid peptide that marks proteins for degradation mainly through the ubiquitin-proteasome system (UPS) and autophagy. Modification by Lys-48-linked poly-Ub chains has been reported as means of selecting proteins for degradation by the UPS. Whereas, Lys-63-linked poly-ubiquitination is associated with the clearance of proteins by autophagy.

My First Professional Meeting Experience

Brandon Chen is a senior majoring in Biology. He was awarded a Fall 201 Conference Grant which he used to attend the American Society of Hematology Annual Meeting.


Trial & Error

Philip Chu is a senior who majoring in Neuroscience and Behavioral Biology. He was awarded a Fall 2018 Independent Grant which he used to conduct research on Renal Cell Cancer under Dr. John Petros. 

Medicine heals people, but research is what advances medicine. The reason I’ve done 
research throughout my undergraduate experience is because I want to constantly contribute to the advancement of medicine. What motivates me in lab is the thought that every experiment is potentially a step closer in benefiting innumerable lives. I view medicine as the present, and research as the future.

Research Profile - Zoe Robbin

Zoe is an Emory senior from Fairfield Connecticut who studies Quantitative Sciences and Arabic. She was the Emory Global Health Institute Field Scholar in 2018 and traveled to Jordan to conduct research on sexual harassment in partnership with the Information and Research Center of the King Hussein Foundation. She worked on a study that seeks to assess the prevalence and develop a primary prevention intervention against sexual harassment at the University of Jordan. A professor from the Rollins School of Public Health is leading this study in partnership with the research team at the King Hussein Foundation. She is continuing her research on sexual harassment in at the University of Jordan through her senior honors thesis. Her argument is that gender-roles in Jordan carryover from tribal institutions into institutions of higher education. She is establishing this link through Sex-role Spillover theory. Zoe’s thesis will also include an epistemological discussion about Orientalism within Women’s Studies and Political Science, which has led scholars on both sides of the spectrum to misinterpret the power of tribalism. When asked about any significant moments through her research, Zoe said, “I was feeling frustrated as I searched the library and the internet for scholarly literature about women’s roles within modern Jordanian tribes. Each article I found left me wanting a more in-depth and politically-removed analysis. In the midst of my frustration, I looked up from my laptop, quietly laughing as I realized that I had found my role in the literature. Suddenly, my thesis was not an academic exercise or a resume item, but instead a meaningful contribution to the field. This night in the library has become my favorite moment in my research process.” Zoe also has two publications: 
(2018) “A Systematic Review of the Current Status of Safer Conception Strategies for HIV           Affected Heterosexual Couples in Sub-Saharan Africa.” J AIDS Behav.
(2018) “Bridging the Gap from Policy to Practice: Diabetes in Rural Morocco.” SIT Digital            Collections.